Kovács, Dóra <br/><br/>
An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.  [electronic resource] 

 -  European journal of medicinal chemistry  2013 
 - 649-60 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2013.10.038  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Androstenes--chemical synthesis<br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclization<br/>Dehydration<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Enzyme Inhibitors--chemical synthesis<br/>HeLa Cells<br/>Humans<br/>MCF-7 Cells<br/>Male<br/>Molecular Conformation<br/>Oximes--chemistry<br/>Rats<br/>Rats, Wistar<br/>Steroid 17-alpha-Hydroxylase--antagonists & inhibitors<br/>Structure-Activity Relationship<br/>Testis--enzymology