TY - GEN AU - Lam,Hilaire C AU - Cloonan,Suzanne M AU - Bhashyam,Abhiram R AU - Haspel,Jeffery A AU - Singh,Anju AU - Sathirapongsasuti,J Fah AU - Cervo,Morgan AU - Yao,Hongwei AU - Chung,Anna L AU - Mizumura,Kenji AU - An,Chang Hyeok AU - Shan,Bin AU - Franks,Jonathan M AU - Haley,Kathleen J AU - Owen,Caroline A AU - Tesfaigzi,Yohannes AU - Washko,George R AU - Quackenbush,John AU - Silverman,Edwin K AU - Rahman,Irfan AU - Kim,Hong Pyo AU - Mahmood,Ashfaq AU - Biswal,Shyam S AU - Ryter,Stefan W AU - Choi,Augustine M K TI - Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction SN - 1558-8238 PY - 2014///0204 KW - Animals KW - Apoptosis Regulatory Proteins KW - deficiency KW - Autophagy KW - physiology KW - Beclin-1 KW - Cells, Cultured KW - Cilia KW - Cytosol KW - enzymology KW - Epithelial Cells KW - ultrastructure KW - Female KW - Histone Deacetylase 6 KW - Histone Deacetylase Inhibitors KW - pharmacology KW - Histone Deacetylases KW - Humans KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Microscopy, Electron, Scanning KW - Microtubule-Associated Proteins KW - Mucus KW - NF-E2-Related Factor 2 KW - Phenotype KW - Phenylbutyrates KW - Proteasome Endopeptidase Complex KW - metabolism KW - Protein Processing, Post-Translational KW - Pulmonary Disease, Chronic Obstructive KW - Sirtuin 1 KW - Tobacco Products KW - Tobacco Smoke Pollution KW - adverse effects KW - Trachea KW - cytology KW - Ubiquitination N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI69636 ER -