Aminzadeh, Mohammad A <br/><br/>
The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease.  [electronic resource] 

 -  Xenobiotica; the fate of foreign compounds in biological systems  Jun 2014 
 - 570-8 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1366-5928 
<br/><br/><label>Standard No.: </label>10.3109/00498254.2013.852705  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Blotting, Western<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Fibrosis<br/>Gene Expression Regulation--drug effects<br/>Inflammation--pathology<br/>Intracellular Signaling Peptides and Proteins--metabolism<br/>Kelch-Like ECH-Associated Protein 1<br/>Kidney--drug effects<br/>Male<br/>NF-E2-Related Factor 2--metabolism<br/>Oleanolic Acid--analogs & derivatives<br/>Oxidative Stress--drug effects<br/>RNA, Messenger--genetics<br/>Rats, Sprague-Dawley<br/>Renal Insufficiency, Chronic--drug therapy<br/>Signal Transduction--drug effects<br/>Smad7 Protein--metabolism<br/>Transforming Growth Factor beta--metabolism