TY  - GEN
AU  - Thomas,Nisha E
AU  - Thamkachy,Reshma
AU  - Sivakumar,Krishnankutty C
AU  - Sreedevi,Krishnakumar J
AU  - Louis,Xavier Lieben
AU  - Thomas,Sannu A
AU  - Kumar,Rohith
AU  - Rajasekharan,Kallikat N
AU  - Cassimeris,Lynne
AU  - Sengupta,Suparna
TI  - Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics
SN  - 1538-8514
PY  - 2014///0929
KW  - Cell Proliferation
KW  - drug effects
KW  - Colchicine
KW  - administration & dosage
KW  - Colonic Neoplasms
KW  - drug therapy
KW  - HCT116 Cells
KW  - Humans
KW  - Hydrogen Bonding
KW  - Microtubules
KW  - Mitosis
KW  - Molecular Dynamics Simulation
KW  - Protein Conformation
KW  - Thiazoles
KW  - Tubulin
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1535-7163.MCT-13-0479
ER  -