Thomas, Nisha E <br/><br/>
Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics.  [electronic resource] 

 -  Molecular cancer therapeutics  Jan 2014 
 - 179-89 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-8514 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-13-0479  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Proliferation--drug effects<br/>Colchicine--administration & dosage<br/>Colonic Neoplasms--drug therapy<br/>HCT116 Cells<br/>Humans<br/>Hydrogen Bonding<br/>Microtubules--drug effects<br/>Mitosis--drug effects<br/>Molecular Dynamics Simulation<br/>Protein Conformation--drug effects<br/>Thiazoles--administration & dosage<br/>Tubulin--chemistry