TY - GEN AU - Zhou,Lei AU - Lovell,Kimberly M AU - Frankowski,Kevin J AU - Slauson,Stephen R AU - Phillips,Angela M AU - Streicher,John M AU - Stahl,Edward AU - Schmid,Cullen L AU - Hodder,Peter AU - Madoux,Franck AU - Cameron,Michael D AU - Prisinzano,Thomas E AU - Aubé,Jeffrey AU - Bohn,Laura M TI - Development of functionally selective, small molecule agonists at kappa opioid receptors SN - 1083-351X PY - 2014///0305 KW - Animals KW - Arrestins KW - metabolism KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Drug Discovery KW - GTP-Binding Proteins KW - Humans KW - Ligands KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Quinolones KW - chemical synthesis KW - Receptors, Opioid, kappa KW - agonists KW - Signal Transduction KW - Triazoles KW - beta-Arrestins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1074/jbc.M113.504381 ER -