TY - GEN AU - Trudu,Matteo AU - Janas,Sylvie AU - Lanzani,Chiara AU - Debaix,Huguette AU - Schaeffer,Céline AU - Ikehata,Masami AU - Citterio,Lorena AU - Demaretz,Sylvie AU - Trevisani,Francesco AU - Ristagno,Giuseppe AU - Glaudemans,Bob AU - Laghmani,Kamel AU - Dell'Antonio,Giacomo AU - Loffing,Johannes AU - Rastaldi,Maria P AU - Manunta,Paolo AU - Devuyst,Olivier AU - Rampoldi,Luca TI - Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression SN - 1546-170X PY - 2014///0227 KW - Adult KW - Aged KW - Animals KW - Female KW - Gene Expression Regulation KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - Humans KW - Hypertension KW - chemically induced KW - Male KW - Mice KW - Mice, Transgenic KW - Middle Aged KW - Polymorphism, Single Nucleotide KW - Promoter Regions, Genetic KW - genetics KW - Renal Insufficiency, Chronic KW - Sodium, Dietary KW - adverse effects KW - Up-Regulation KW - Uromodulin KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nm.3384 ER -