TY - GEN AU - Jurutka,Peter W AU - Kaneko,Ichiro AU - Yang,Joanna AU - Bhogal,Jaskaran S AU - Swierski,Johnathon C AU - Tabacaru,Christa R AU - Montano,Luis A AU - Huynh,Chanh C AU - Jama,Rabia A AU - Mahelona,Ryan D AU - Sarnowski,Joseph T AU - Marcus,Lisa M AU - Quezada,Alexis AU - Lemming,Brittney AU - Tedesco,Maria A AU - Fischer,Audra J AU - Mohamed,Said A AU - Ziller,Joseph W AU - Ma,Ning AU - Gray,Geoffrey M AU - van der Vaart,Arjan AU - Marshall,Pamela A AU - Wagner,Carl E TI - Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254) SN - 1520-4804 PY - 2014///0318 KW - Coumaric Acids KW - chemical synthesis KW - Crystallography, X-Ray KW - Dose-Response Relationship, Drug KW - Humans KW - Models, Molecular KW - Molecular Structure KW - Retinoid X Receptors KW - agonists KW - Structure-Activity Relationship KW - Tetrahydronaphthalenes N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/jm4008517 ER -