TY - GEN AU - Cortes,J E AU - Kim,D-W AU - Pinilla-Ibarz,J AU - le Coutre,P AU - Paquette,R AU - Chuah,C AU - Nicolini,F E AU - Apperley,J F AU - Khoury,H J AU - Talpaz,M AU - DiPersio,J AU - DeAngelo,D J AU - Abruzzese,E AU - Rea,D AU - Baccarani,M AU - Müller,M C AU - Gambacorti-Passerini,C AU - Wong,S AU - Lustgarten,S AU - Rivera,V M AU - Clackson,T AU - Turner,C D AU - Haluska,F G AU - Guilhot,F AU - Deininger,M W AU - Hochhaus,A AU - Hughes,T AU - Goldman,J M AU - Shah,N P AU - Kantarjian,H TI - A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias SN - 1533-4406 PY - 2013///1112 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Female KW - Humans KW - Imidazoles KW - adverse effects KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - drug therapy KW - Male KW - Middle Aged KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Protein Kinase Inhibitors KW - Pyridazines KW - Thrombocytopenia KW - chemically induced KW - Thrombosis KW - Young Adult N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1056/NEJMoa1306494 ER -