TY - GEN AU - Chatelain,Franck C AU - Bichet,Delphine AU - Feliciangeli,Sylvain AU - Larroque,Marie-Madeleine AU - Braud,Véronique M AU - Douguet,Dominique AU - Lesage,Florian TI - Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane SN - 1083-351X PY - 2014///0213 KW - Amino Acid Sequence KW - Amino Acid Substitution KW - Animals KW - Cell Membrane KW - metabolism KW - Dogs KW - Endoplasmic Reticulum KW - Female KW - Gene Silencing KW - Humans KW - Intracellular Space KW - Madin Darby Canine Kidney Cells KW - Membrane Potentials KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Oocytes KW - Phosphorylation KW - Potassium Channels, Tandem Pore Domain KW - chemistry KW - Protein Structure, Secondary KW - Recombinant Proteins KW - Sequence Homology, Amino Acid KW - Xenopus laevis N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M113.503318 ER -