TY - GEN AU - Teufel,Robin AU - Miyanaga,Akimasa AU - Michaudel,Quentin AU - Stull,Frederick AU - Louie,Gordon AU - Noel,Joseph P AU - Baran,Phil S AU - Palfey,Bruce AU - Moore,Bradley S TI - Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement SN - 1476-4687 PY - 2013///1223 KW - Anti-Bacterial Agents KW - biosynthesis KW - Bacterial Proteins KW - chemistry KW - Biocatalysis KW - Bridged-Ring Compounds KW - metabolism KW - Crystallography, X-Ray KW - Cyclization KW - Flavins KW - Flavoproteins KW - Isotope Labeling KW - Mixed Function Oxygenases KW - Models, Chemical KW - Models, Molecular KW - Oxidation-Reduction KW - Polyketides KW - Protein Conformation KW - Streptomyces KW - enzymology KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/nature12643 ER -