TY - GEN AU - Neumann,Jennifer AU - Boerries,Melanie AU - Köhler,Rebecca AU - Giaisi,Marco AU - Krammer,Peter H AU - Busch,Hauke AU - Li-Weber,Min TI - The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints SN - 1097-0215 PY - 2014///0515 KW - Antineoplastic Agents KW - pharmacology KW - Ataxia Telangiectasia Mutated Proteins KW - drug effects KW - Benzofurans KW - Cell Line, Tumor KW - Cell Proliferation KW - Checkpoint Kinase 1 KW - Checkpoint Kinase 2 KW - genetics KW - DNA Damage KW - HCT116 Cells KW - HT29 Cells KW - Hep G2 Cells KW - Humans KW - Jurkat Cells KW - Leukemia KW - drug therapy KW - MCF-7 Cells KW - Phosphorylation KW - Plant Extracts KW - Protein Biosynthesis KW - Protein Kinases KW - RNA Interference KW - RNA, Small Interfering KW - S Phase Cell Cycle Checkpoints KW - T-Lymphocytes KW - cdc25 Phosphatases KW - biosynthesis N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/ijc.28521 ER -