TY - GEN AU - Huang,Liu AU - Zhang,Tao AU - Xie,Conghua AU - Liao,Xin AU - Yu,Qianqian AU - Feng,Jueping AU - Ma,Hong AU - Dai,Jing AU - Li,Min AU - Chen,Jigui AU - Zang,Aihua AU - Wang,Qian AU - Ge,Shuwang AU - Qin,Kai AU - Cai,Juan AU - Yuan,Xianglin TI - SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer SN - 1932-6203 PY - 2014///0617 KW - Adolescent KW - Adult KW - Aged KW - Antineoplastic Agents KW - pharmacology KW - Antineoplastic Combined Chemotherapy Protocols KW - Camptothecin KW - analogs & derivatives KW - Colorectal Neoplasms KW - drug therapy KW - Female KW - Haplotypes KW - Humans KW - Irinotecan KW - Linkage Disequilibrium KW - Liver-Specific Organic Anion Transporter 1 KW - Male KW - Middle Aged KW - Neoplasm Metastasis KW - Organic Anion Transporters KW - genetics KW - Pharmacogenetics KW - Polymorphism, Single Nucleotide KW - Prospective Studies KW - Pyrimidines KW - chemistry KW - Reduced Folate Carrier Protein KW - Survival Analysis KW - Time Factors KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0077223 ER -