TY - GEN AU - Chretien,Anne-Sophie AU - Harlé,Alexandre AU - Meyer-Lefebvre,Magali AU - Rouyer,Marie AU - Husson,Marie AU - Ramacci,Carole AU - Harter,Valentin AU - Genin,Pascal AU - Leroux,Agnès AU - Merlin,Jean-Louis TI - Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer SN - 2045-7634 PY - 2014///0519 KW - Adult KW - Aged KW - Aged, 80 and over KW - Colorectal Neoplasms KW - drug therapy KW - DNA Mutational Analysis KW - methods KW - DNA, Neoplasm KW - genetics KW - Female KW - Humans KW - Male KW - Middle Aged KW - Molecular Targeted Therapy KW - Mutation KW - Neoplasm Metastasis KW - Nucleic Acid Denaturation KW - Patient Selection KW - Polymerase Chain Reaction KW - Polymorphism, Restriction Fragment Length KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins p21(ras) KW - Sensitivity and Specificity KW - Young Adult KW - ras Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/cam4.47 ER -