TY - GEN AU - Pal,Harish Chandra AU - Sharma,Samriti AU - Strickland,Leah Ray AU - Agarwal,Jyoti AU - Athar,Mohammad AU - Elmets,Craig A AU - Afaq,Farrukh TI - Delphinidin reduces cell proliferation and induces apoptosis of non-small-cell lung cancer cells by targeting EGFR/VEGFR2 signaling pathways SN - 1932-6203 PY - 2014///0522 KW - Animals KW - Anthocyanins KW - administration & dosage KW - Antineoplastic Agents, Phytogenic KW - Apoptosis KW - drug effects KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Caspases KW - metabolism KW - Cell Line, Tumor KW - Cell Proliferation KW - Cyclin D1 KW - Disease Models, Animal KW - Epidermal Growth Factor KW - pharmacology KW - ErbB Receptors KW - Female KW - Humans KW - Lung Neoplasms KW - Mice KW - Mitogen-Activated Protein Kinases KW - Neovascularization, Pathologic KW - Phosphatidylinositol 3-Kinases KW - Phosphorylation KW - Poly(ADP-ribose) Polymerases KW - Proliferating Cell Nuclear Antigen KW - Proteolysis KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-bcl-2 KW - Signal Transduction KW - Tumor Burden KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factor Receptor-2 KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0077270 ER -