TY  - GEN
AU  - Bridgeman,J S
AU  - Ladell,K
AU  - Sheard,V E
AU  - Miners,K
AU  - Hawkins,R E
AU  - Price,D A
AU  - Gilham,D E
TI  - CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy
SN  - 1365-2249
PY  - 2014///0604
KW  - Antigens, CD
KW  - metabolism
KW  - Antigens, Differentiation, T-Lymphocyte
KW  - Antigens, Neoplasm
KW  - immunology
KW  - CD3 Complex
KW  - genetics
KW  - Cell Line
KW  - HEK293 Cells
KW  - Humans
KW  - Immunoreceptor Tyrosine-Based Activation Motif
KW  - Immunotherapy, Adoptive
KW  - methods
KW  - Jurkat Cells
KW  - Lectins, C-Type
KW  - Lymphocyte Activation
KW  - Neoplasms
KW  - Receptors, Antigen, T-Cell
KW  - Recombinant Fusion Proteins
KW  - Signal Transduction
KW  - T-Lymphocytes
KW  - Transcriptional Activation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/cei.12216
ER  -