Bridgeman, J S <br/><br/>
CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy.  [electronic resource] 

 -  Clinical and experimental immunology  Feb 2014 
 - 258-67 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1365-2249 
<br/><br/><label>Standard No.: </label>10.1111/cei.12216  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antigens, CD--metabolism<br/>Antigens, Differentiation, T-Lymphocyte--metabolism<br/>Antigens, Neoplasm--immunology<br/>CD3 Complex--genetics<br/>Cell Line<br/>HEK293 Cells<br/>Humans<br/>Immunoreceptor Tyrosine-Based Activation Motif--genetics<br/>Immunotherapy, Adoptive--methods<br/>Jurkat Cells<br/>Lectins, C-Type--metabolism<br/>Lymphocyte Activation<br/>Neoplasms--immunology<br/>Receptors, Antigen, T-Cell--genetics<br/>Recombinant Fusion Proteins--genetics<br/>Signal Transduction--immunology<br/>T-Lymphocytes--immunology<br/>Transcriptional Activation--genetics