TY - GEN AU - Kang,Bo-Rui AU - Shan,Ai-Lin AU - Li,Yi-Ping AU - Xu,Jing AU - Lu,She-Min AU - Zhang,San-Qi TI - Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping SN - 1464-3391 PY - 2014///0514 KW - Antineoplastic Agents KW - chemistry KW - Binding Sites KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Drug Evaluation, Preclinical KW - ErbB Receptors KW - antagonists & inhibitors KW - Humans KW - Isoquinolines KW - Molecular Docking Simulation KW - Protein Binding KW - Protein Kinase Inhibitors KW - Protein Structure, Tertiary KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmc.2013.09.027 ER -