Kang, Bo-Rui <br/><br/>
Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Nov 2013 
 - 6956-64 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2013.09.027  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Binding Sites<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Drug Evaluation, Preclinical<br/>ErbB Receptors--antagonists & inhibitors<br/>Humans<br/>Isoquinolines--chemistry<br/>Molecular Docking Simulation<br/>Protein Binding--drug effects<br/>Protein Kinase Inhibitors--chemistry<br/>Protein Structure, Tertiary<br/>Structure-Activity Relationship