TY - GEN AU - Kalous,Ondrej AU - Conklin,Dylan AU - Desai,Amrita J AU - Dering,Judy AU - Goldstein,Jennifer AU - Ginther,Charles AU - Anderson,Lee AU - Lu,Ming AU - Kolarova,Teodora AU - Eckardt,Mark A AU - Langerød,Anita AU - Børresen-Dale,Anne-Lise AU - Slamon,Dennis J AU - Finn,Richard S TI - AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53 SN - 1573-7217 PY - 2014///0527 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Aurora Kinase A KW - antagonists & inhibitors KW - Aurora Kinase B KW - Aurora Kinase C KW - Breast Neoplasms KW - Cell Cycle KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Cyclin-Dependent Kinase Inhibitor p21 KW - metabolism KW - DNA Copy Number Variations KW - DNA Mutational Analysis KW - Drug Screening Assays, Antitumor KW - Female KW - Gene Expression KW - Humans KW - Mutation KW - Phthalazines KW - Tumor Suppressor Protein p53 KW - genetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1007/s10549-013-2702-z ER -