TY - GEN AU - Donnell,Andrew F AU - Michoud,Christophe AU - Rupert,Kenneth C AU - Han,Xiaochun AU - Aguilar,Douglas AU - Frank,Karl B AU - Fretland,Adrian J AU - Gao,Lin AU - Goggin,Barry AU - Hogg,J Heather AU - Hong,Kyoungja AU - Janson,Cheryl A AU - Kester,Robert F AU - Kong,Norman AU - Le,Kang AU - Li,Shirley AU - Liang,Weiling AU - Lombardo,Louis J AU - Lou,Yan AU - Lukacs,Christine M AU - Mischke,Steven AU - Moliterni,John A AU - Polonskaia,Ann AU - Schutt,Andrew D AU - Solis,Dave S AU - Specian,Anthony AU - Taylor,Robert T AU - Weisel,Martin AU - Remiszewski,Stacy W TI - Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain SN - 1520-4804 PY - 2014///0310 KW - Alanine KW - analogs & derivatives KW - Animals KW - Antibodies, Monoclonal KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Caspase 3 KW - metabolism KW - Caspase 7 KW - Cell Line, Tumor KW - Cell Survival KW - Crystallography, X-Ray KW - Female KW - Heterocyclic Compounds KW - chemical synthesis KW - Humans KW - Inhibitor of Apoptosis Proteins KW - antagonists & inhibitors KW - Mice KW - Mice, Nude KW - Models, Chemical KW - Models, Molecular KW - Molecular Structure KW - Oxazepines KW - Protein Structure, Tertiary KW - Rats KW - Ubiquitin-Protein Ligases KW - X-Linked Inhibitor of Apoptosis Protein KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm400731m ER -