Allouch, Awatef

p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Oct 2013 - E3997-4006 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1306719110 doi


Cells, Cultured
Cyclin-Dependent Kinase Inhibitor p21--genetics
DNA, Complementary--biosynthesis
DNA, Viral--biosynthesis
Deoxyribonucleotides--biosynthesis
Down-Regulation--genetics
E2F1 Transcription Factor--genetics
Gene Expression Regulation, Enzymologic
HIV Infections--metabolism
HIV-1--physiology
Macrophages--metabolism
Monomeric GTP-Binding Proteins--genetics
Ribonucleotide Reductases--biosynthesis
SAM Domain and HD Domain-Containing Protein 1
Simian Immunodeficiency Virus--physiology
Transcription, Genetic--genetics
Virus Replication--physiology