Jahchan, Nadine S

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. [electronic resource] - Cancer discovery Dec 2013 - 1364-77 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

2159-8290

10.1158/2159-8290.CD-13-0183 doi


Animals
Antidepressive Agents, Tricyclic--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Computational Biology
Drug Repositioning
Humans
Lung Neoplasms--drug therapy
Mice
Neuroendocrine Tumors--drug therapy
Receptors, G-Protein-Coupled--antagonists & inhibitors
Small Cell Lung Carcinoma--drug therapy
Xenograft Model Antitumor Assays