TY  - GEN
AU  - Gupta,Subash C
AU  - Francis,Sajin K
AU  - Nair,Mangalam S
AU  - Mo,Yin-Yuan
AU  - Aggarwal,Bharat B
TI  - Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway
SN  - 1083-351X
PY  - 2014///0120
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis Regulatory Proteins
KW  - biosynthesis
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - drug effects
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - genetics
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Limonins
KW  - MAP Kinase Signaling System
KW  - Neoplasms
KW  - drug therapy
KW  - Reactive Oxygen Species
KW  - metabolism
KW  - Receptors, TNF-Related Apoptosis-Inducing Ligand
KW  - Response Elements
KW  - TNF-Related Apoptosis-Inducing Ligand
KW  - Transcription Factor CHOP
KW  - Tumor Suppressor Protein p53
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M113.455188
ER  -