Borodovsky, Alexandra

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. [electronic resource] - Oncotarget Oct 2013 - 1737-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.1408 doi


Animals
Antimetabolites, Antineoplastic--pharmacology
Azacitidine--pharmacology
Brain Neoplasms--drug therapy
Cell Differentiation--drug effects
Cell Growth Processes--drug effects
Cell Line, Tumor
DNA Methylation--drug effects
Female
Glioma--drug therapy
Humans
Immunohistochemistry
Isocitrate Dehydrogenase--genetics
Male
Mice
Mice, Nude
Mutation
Xenograft Model Antitumor Assays