TY - GEN AU - Chen,Jun-Jiang AU - Patel,Atish AU - Sodani,Kamlesh AU - Xiao,Zhi-Jie AU - Tiwari,Amit K AU - Zhang,Dong-Mei AU - Li,Ying-Jie AU - Yang,Dong-Hua AU - Ye,Wen-Cai AU - Chen,Si-Dong AU - Chen,Zhe-Sheng TI - bba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10) SN - 1932-6203 PY - 2014///0508 KW - ATP Binding Cassette Transporter, Subfamily B KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - genetics KW - Adenosine Triphosphate KW - metabolism KW - Antineoplastic Agents KW - Cell Line, Tumor KW - Drug Resistance, Multiple KW - Drug Resistance, Neoplasm KW - Gene Expression KW - HEK293 Cells KW - Humans KW - Inhibitory Concentration 50 KW - Multidrug Resistance-Associated Proteins KW - antagonists & inhibitors KW - Paclitaxel KW - Pentacyclic Triterpenes KW - Protein Transport KW - drug effects KW - Triterpenes KW - chemistry KW - Betulinic Acid N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0074573 ER -