TY  - GEN
AU  - Kapoor,Khyati
AU  - Bhatnagar,Jaya
AU  - Chufan,Eduardo E
AU  - Ambudkar,Suresh V
TI  - Mutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone Hsp70
SN  - 1083-351X
PY  - 2014///0120
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - genetics
KW  - Aspartic Acid
KW  - Biological Transport, Active
KW  - drug effects
KW  - Cyclosporine
KW  - pharmacology
KW  - Endoplasmic Reticulum
KW  - HSP70 Heat-Shock Proteins
KW  - HeLa Cells
KW  - Humans
KW  - Immunosuppressive Agents
KW  - Mutation
KW  - Protein Folding
KW  - Protein Structure, Secondary
KW  - Protein Structure, Tertiary
KW  - Tacrolimus
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1074/jbc.M113.498980
ER  -