Kapoor, Khyati <br/><br/>
Mutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone Hsp70.  [electronic resource] 

 -  The Journal of biological chemistry  Nov 2013 
 - 32622-32636 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1083-351X 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M113.498980  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B<br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics<br/>Aspartic Acid--genetics<br/>Biological Transport, Active--drug effects<br/>Cyclosporine--pharmacology<br/>Endoplasmic Reticulum--genetics<br/>HSP70 Heat-Shock Proteins--genetics<br/>HeLa Cells<br/>Humans<br/>Immunosuppressive Agents--pharmacology<br/>Mutation<br/>Protein Folding--drug effects<br/>Protein Structure, Secondary<br/>Protein Structure, Tertiary<br/>Tacrolimus--pharmacology