TY - GEN AU - Deng,Q AU - Yu,X AU - Xiao,L AU - Hu,Z AU - Luo,X AU - Tao,Y AU - Yang,L AU - Liu,X AU - Chen,H AU - Ding,Z AU - Feng,T AU - Tang,Y AU - Weng,X AU - Gao,J AU - Yi,W AU - Bode,A M AU - Dong,Z AU - Liu,J AU - Cao,Y TI - Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway SN - 2041-4889 PY - 2014///0312 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - metabolism KW - Adenosine Triphosphate KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Autophagy KW - drug effects KW - Carcinoma KW - Cell Death KW - Cell Line, Tumor KW - Cell Proliferation KW - Disease Models, Animal KW - Down-Regulation KW - Drug Screening Assays, Antitumor KW - Energy Metabolism KW - Glucose KW - Hexokinase KW - Mice KW - Mice, Nude KW - Models, Biological KW - Nasopharyngeal Carcinoma KW - Nasopharyngeal Neoplasms KW - drug therapy KW - Necrosis KW - Neoplasms KW - Phosphatidylinositol 3-Kinases KW - Proto-Oncogene Proteins c-akt KW - Sesquiterpenes KW - Signal Transduction KW - Substrate Specificity KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/cddis.2013.324 ER -