BMP4 is involved in the chemoresistance of myeloid leukemia cells through regulating autophagy-apoptosis balance. [electronic resource]
- Cancer investigation Oct 2013
- 555-62 p. digital
Publication Type: Journal Article
1532-4192
10.3109/07357907.2013.834925 doi
Animals Antimetabolites, Antineoplastic--pharmacology Apoptosis Apoptosis Regulatory Proteins--biosynthesis Autophagy Autophagy-Related Protein 5 Beclin-1 Bone Morphogenetic Protein 4--genetics CDC2 Protein Kinase--biosynthesis Caspase 2--metabolism Caspase 3--metabolism Caspase 9--metabolism Cell Line, Tumor Cell Proliferation Cyclin B1--biosynthesis Cytarabine--pharmacology Drug Resistance, Neoplasm Enzyme Activation Female Humans Leukemia, Myeloid--drug therapy Membrane Proteins--biosynthesis Mice Mice, Nude Microtubule-Associated Proteins--biosynthesis Neoplasm Transplantation RNA Interference RNA, Small Interfering Up-Regulation Xenograft Model Antitumor Assays