Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations. [electronic resource]
- The American journal of gastroenterology Nov 2013
- 1785-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1572-0241
10.1038/ajg.2013.292 doi
Aged Aged, 80 and over Cell Cycle Proteins--genetics Chromosome Aberrations Class I Phosphatidylinositol 3-Kinases Colorectal Neoplasms--genetics DNA Mutational Analysis Disease-Free Survival F-Box Proteins--genetics F-Box-WD Repeat-Containing Protein 7 Female GTP Phosphohydrolases--genetics Humans Loss of Heterozygosity Male Membrane Proteins--genetics Microsatellite Instability Middle Aged Mutation Neoplasm Staging Phosphatidylinositol 3-Kinases--genetics Prognosis Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins p21(ras) Survival Rate Tumor Suppressor Protein p53--genetics Ubiquitin-Protein Ligases--genetics ras Proteins--genetics