TY  - GEN
AU  - Doussau,Adélaïde
AU  - Thiébaut,Rodolphe
AU  - Paoletti,Xavier
TI  - Dose-finding design using mixed-effect proportional odds model for longitudinal graded toxicity data in phase I oncology clinical trials
SN  - 1097-0258
PY  - 2014///0804
KW  - Adult
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Clinical Trials, Phase I as Topic
KW  - methods
KW  - Computer Simulation
KW  - Humans
KW  - Likelihood Functions
KW  - Longitudinal Studies
KW  - Maximum Tolerated Dose
KW  - Models, Statistical
KW  - Neoplasms
KW  - drug therapy
KW  - Plant Preparations
KW  - Ribosome Inactivating Proteins, Type 2
KW  - Toxins, Biological
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/sim.5960
ER  -