TY  - GEN
AU  - Maurer,Britta
AU  - Distler,Alfiya
AU  - Dees,Clara
AU  - Khan,Korsa
AU  - Denton,Christopher P
AU  - Abraham,David
AU  - Gay,Renate E
AU  - Michel,Beat A
AU  - Gay,Steffen
AU  - Hw Distler,Jörg
AU  - Distler,Oliver
TI  - Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors
SN  - 1468-2060
PY  - 2014///0120
KW  - Adult
KW  - Animals
KW  - Benzamides
KW  - therapeutic use
KW  - Biopsy
KW  - Bleomycin
KW  - Disease Models, Animal
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Female
KW  - Fibrosis
KW  - Fos-Related Antigen-2
KW  - genetics
KW  - Humans
KW  - Imatinib Mesylate
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Middle Aged
KW  - Molecular Targeted Therapy
KW  - Piperazines
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Protein-Tyrosine Kinases
KW  - antagonists & inhibitors
KW  - Proto-Oncogene Proteins c-abl
KW  - metabolism
KW  - Proto-Oncogene Proteins c-sis
KW  - Pyrimidines
KW  - Scleroderma, Systemic
KW  - drug therapy
KW  - Skin
KW  - Treatment Outcome
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1136/annrheumdis-2013-203729
ER  -