Tsakiri, Eleni N

Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. [electronic resource] - Free radical biology & medicine Dec 2013 - 1155-1163 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-4596

10.1016/j.freeradbiomed.2013.08.186 doi


Aging--drug effects
Albumins--chemistry
Animals
Animals, Genetically Modified
Cathepsin B--biosynthesis
Cathepsin D--genetics
Cathepsin L--biosynthesis
Diet
Drosophila melanogaster--metabolism
Fructose--chemistry
Glucose--chemistry
Glycation End Products, Advanced--administration & dosage
Glycosylation
Lipofuscin--administration & dosage
Longevity--drug effects
Oxidation-Reduction
Oxidative Stress--drug effects
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors
Protein Folding--drug effects
RNA Interference
RNA, Small Interfering
Ribose--chemistry
Up-Regulation