TY  - GEN
AU  - Wartlick,Friedrich
AU  - Bopp,Anita
AU  - Henninger,Christian
AU  - Fritz,Gerhard
TI  - DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac
SN  - 0006-3002
PY  - 2014///0224
KW  - Active Transport, Cell Nucleus
KW  - drug effects
KW  - Animals
KW  - Antigens, Neoplasm
KW  - metabolism
KW  - Cell Death
KW  - Cell Line
KW  - Cell Nucleus
KW  - Cytoprotection
KW  - DNA Damage
KW  - DNA Topoisomerases, Type II
KW  - DNA-Binding Proteins
KW  - antagonists & inhibitors
KW  - Doxorubicin
KW  - pharmacology
KW  - G2 Phase
KW  - HSP90 Heat-Shock Proteins
KW  - Humans
KW  - Phosphorylation
KW  - Protein Binding
KW  - Protein Kinase Inhibitors
KW  - Pyrones
KW  - Quinolines
KW  - Rats
KW  - S Phase
KW  - Signal Transduction
KW  - Topoisomerase II Inhibitors
KW  - Tumor Suppressor Protein p53
KW  - rac GTP-Binding Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bbamcr.2013.08.016
ER  -