Wartlick, Friedrich <br/><br/>
DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac.  [electronic resource] 

 -  Biochimica et biophysica acta  Dec 2013 
 - 3093-3103 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-3002 
<br/><br/><label>Standard No.: </label>10.1016/j.bbamcr.2013.08.016  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Active Transport, Cell Nucleus--drug effects<br/>Animals<br/>Antigens, Neoplasm--metabolism<br/>Cell Death--drug effects<br/>Cell Line<br/>Cell Nucleus--drug effects<br/>Cytoprotection--drug effects<br/>DNA Damage<br/>DNA Topoisomerases, Type II--metabolism<br/>DNA-Binding Proteins--antagonists & inhibitors<br/>Doxorubicin--pharmacology<br/>G2 Phase--drug effects<br/>HSP90 Heat-Shock Proteins--metabolism<br/>Humans<br/>Phosphorylation--drug effects<br/>Protein Binding--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Pyrones--pharmacology<br/>Quinolines--pharmacology<br/>Rats<br/>S Phase--drug effects<br/>Signal Transduction--drug effects<br/>Topoisomerase II Inhibitors--pharmacology<br/>Tumor Suppressor Protein p53--metabolism<br/>rac GTP-Binding Proteins--antagonists & inhibitors