TY - GEN AU - Hann,Swei Sunny AU - Chen,Jianping AU - Wang,Zhiyu AU - Wu,Jingjing AU - Zheng,Fang AU - Zhao,Shunyu TI - Targeting EP4 by curcumin through cross talks of AMP-dependent kinase alpha and p38 mitogen-activated protein kinase signaling: the role of PGC-1α and Sp1 SN - 1873-3913 PY - 2014///1203 KW - Adenylate Kinase KW - metabolism KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Curcumin KW - Down-Regulation KW - Enzyme Activation KW - Gene Expression Regulation, Neoplastic KW - Head and Neck Neoplasms KW - drug therapy KW - Humans KW - Metformin KW - Molecular Targeted Therapy KW - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha KW - RNA Interference KW - Receptors, Prostaglandin E, EP4 Subtype KW - genetics KW - Signal Transduction KW - Transcription Factors KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cellsig.2013.08.020 ER -