Leung, Chun Yuen <br/><br/>
Thienopyrimidine bisphosphonate (ThPBP) inhibitors of the human farnesyl pyrophosphate synthase: optimization and characterization of the mode of inhibition.  [electronic resource] 

 -  Journal of medicinal chemistry  Oct 2013 
 - 7939-50 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm400946f  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Catalytic Domain<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Crystallography, X-Ray<br/>Diphosphates--chemistry<br/>Diphosphonates--chemistry<br/>Enzyme Inhibitors--chemistry<br/>Geranyltranstransferase--antagonists & inhibitors<br/>Humans<br/>Models, Molecular<br/>Molecular Structure<br/>Protein Binding<br/>Protein Conformation<br/>Protein Structure, Tertiary<br/>Pyrimidines--chemistry