TY - GEN AU - Gentry,Sara N AU - Jackson,Trachette L TI - A mathematical model of cancer stem cell driven tumor initiation: implications of niche size and loss of homeostatic regulatory mechanisms SN - 1932-6203 PY - 2014///0422 KW - Carcinogenesis KW - Cell Division KW - Cell Line, Tumor KW - Cell Lineage KW - Cell Proliferation KW - Cell Transformation, Neoplastic KW - DNA Mutational Analysis KW - Homeostasis KW - Humans KW - Models, Theoretical KW - Mutation KW - Neoplasms KW - metabolism KW - Neoplastic Stem Cells KW - cytology KW - Point Mutation KW - Probability KW - Signal Transduction KW - Stem Cell Niche N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0071128 ER -