Desimone, Michelle C

Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. [electronic resource] - Journal of the National Cancer Institute Sep 2013 - 1355-64 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1460-2105

10.1093/jnci/djt226 doi


Animals
Apoptosis
Arginine
Ataxia Telangiectasia Mutated Proteins
Carcinoma, Renal Cell--genetics
Cell Cycle Proteins--metabolism
DNA Damage
DNA-Binding Proteins--metabolism
Embryonic Stem Cells
Glutamine
Humans
Hypoxia-Inducible Factor 1--metabolism
Immunohistochemistry
Kidney Neoplasms--genetics
Mice
Occupational Exposure
Point Mutation
Proline
Protein Array Analysis
Protein Serine-Threonine Kinases--metabolism
Serine
Teratoma--genetics
Trichloroethylene--toxicity
Tumor Suppressor Proteins--metabolism
Ubiquitin-Protein Ligases--metabolism
Von Hippel-Lindau Tumor Suppressor Protein--genetics