TY - GEN AU - Xiao,Guiran AU - Fan,Qiangwang AU - Wang,Xiaoxi AU - Zhou,Bing TI - Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding SN - 1091-6490 PY - 2013///1210 KW - Amino Acid Substitution KW - Animals KW - Animals, Genetically Modified KW - Brain KW - metabolism KW - Cation Transport Proteins KW - antagonists & inhibitors KW - Copper KW - administration & dosage KW - Copper-Transporting ATPases KW - Disease Models, Animal KW - Drosophila Proteins KW - Drosophila melanogaster KW - genetics KW - Female KW - Gene Expression KW - Genes, Insect KW - Humans KW - Huntingtin Protein KW - Huntington Disease KW - etiology KW - Nerve Tissue Proteins KW - Peptides KW - Protein Binding KW - RNA Interference KW - Recombinant Proteins KW - Trinucleotide Repeat Expansion N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1308535110 ER -