TY - GEN AU - Zhu,Shunqin AU - Yan,Xiaomin AU - Xiang,Zhonghuai AU - Ding,Han-Fei AU - Cui,Hongjuan TI - Leflunomide reduces proliferation and induces apoptosis in neuroblastoma cells in vitro and in vivo SN - 1932-6203 PY - 2014///0408 KW - Animals KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Dihydroorotate Dehydrogenase KW - Disease Models, Animal KW - Down-Regulation KW - Humans KW - Isoxazoles KW - pharmacology KW - Leflunomide KW - Mice KW - Mice, SCID KW - Neuroblastoma KW - enzymology KW - Oxidoreductases Acting on CH-CH Group Donors KW - metabolism KW - S Phase KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0071555 ER -