TY - GEN AU - Mahesh Kumar,Jerald AU - Idris,Mohammed M AU - Srinivas,Gunda AU - Vinay Kumar,Pallerla AU - Meghah,Vuppalapaty AU - Kavitha,Mitta AU - Reddy,Chada Raji AU - Mainkar,Prathama S AU - Pal,Biswajit AU - Chandrasekar,Srivari AU - Nagesh,Narayana TI - Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine SN - 1932-6203 PY - 2014///0408 KW - Animals KW - Antineoplastic Agents KW - chemical synthesis KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Click Chemistry KW - DNA Fragmentation KW - DNA, Neoplasm KW - antagonists & inhibitors KW - G-Quadruplexes KW - Humans KW - Ligands KW - Melanoma, Experimental KW - chemistry KW - Mice KW - Mice, Inbred C57BL KW - Skin Neoplasms KW - Thymidine KW - Triazoles KW - Tumor Burden KW - Zidovudine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0070798 ER -