Guo, Wenchang <br/><br/>
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors.  [electronic resource] 

 -  PloS one  2013 
 - e70910 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0070910  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Triphosphate--metabolism<br/>Animals<br/>Apoptosis--drug effects<br/>Benzofurans--pharmacology<br/>Binding Sites<br/>Cell Movement--drug effects<br/>Cell Proliferation--drug effects<br/>Disease Models, Animal<br/>Drug Resistance, Neoplasm--genetics<br/>Enzyme Activation--drug effects<br/>Human Umbilical Vein Endothelial Cells--drug effects<br/>Humans<br/>Male<br/>Mice<br/>Models, Molecular<br/>Phosphorylation--drug effects<br/>Prostatic Neoplasms--metabolism<br/>Protein Binding<br/>Protein Conformation<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-myc--antagonists & inhibitors<br/>Quinoxalines--pharmacology<br/>STAT3 Transcription Factor--metabolism<br/>Signal Transduction--drug effects<br/>Xenograft Model Antitumor Assays<br/>src-Family Kinases--antagonists & inhibitors