Puthiyachirakkal, M Thrombin weakens the amnion extracellular matrix (ECM) directly rather than through protease activated receptors. [electronic resource] - Placenta Oct 2013 - 924-31 p. digital Publication Type: Journal Article ISSN: 1532-3102 Standard No.: 10.1016/j.placenta.2013.07.064 doi Subjects--Topical Terms: Amnion--drug effectsExtracellular Matrix--drug effectsFemaleFetal Membranes, Premature Rupture--etiologyHirudins--pharmacologyHumansPregnancyReceptors, Proteinase-Activated--metabolismThrombin--antagonists & inhibitors