TY  - GEN
AU  - Chang,Yong S
AU  - Graves,Bradford
AU  - Guerlavais,Vincent
AU  - Tovar,Christian
AU  - Packman,Kathryn
AU  - To,Kwong-Him
AU  - Olson,Karen A
AU  - Kesavan,Kamala
AU  - Gangurde,Pranoti
AU  - Mukherjee,Aditi
AU  - Baker,Theresa
AU  - Darlak,Krzysztof
AU  - Elkin,Carl
AU  - Filipovic,Zoran
AU  - Qureshi,Farooq Z
AU  - Cai,Hongliang
AU  - Berry,Pamela
AU  - Feyfant,Eric
AU  - Shi,Xiangguo E
AU  - Horstick,James
AU  - Annis,D Allen
AU  - Manning,Anthony M
AU  - Fotouhi,Nader
AU  - Nash,Huw
AU  - Vassilev,Lyubomir T
AU  - Sawyer,Tomi K
TI  - Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
SN  - 1091-6490
PY  - 2013///1216
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Area Under Curve
KW  - Binding, Competitive
KW  - Cell Line, Tumor
KW  - Crystallography, X-Ray
KW  - Female
KW  - HCT116 Cells
KW  - Humans
KW  - MCF-7 Cells
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Models, Molecular
KW  - Neoplasms
KW  - drug therapy
KW  - Peptides
KW  - Peptides, Cyclic
KW  - Protein Binding
KW  - Protein Conformation
KW  - Protein Structure, Secondary
KW  - Proto-Oncogene Proteins c-mdm2
KW  - antagonists & inhibitors
KW  - Rats
KW  - Rats, Long-Evans
KW  - Tumor Suppressor Protein p53
KW  - metabolism
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1073/pnas.1303002110
ER  -