Chang, Yong S <br/><br/>
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Sep 2013 
 - E3445-54 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1303002110  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Area Under Curve<br/>Binding, Competitive<br/>Cell Line, Tumor<br/>Crystallography, X-Ray<br/>Female<br/>HCT116 Cells<br/>Humans<br/>MCF-7 Cells<br/>Male<br/>Mice<br/>Mice, Nude<br/>Models, Molecular<br/>Neoplasms--drug therapy<br/>Peptides--chemistry<br/>Peptides, Cyclic--chemistry<br/>Protein Binding<br/>Protein Conformation<br/>Protein Structure, Secondary<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Rats<br/>Rats, Long-Evans<br/>Tumor Suppressor Protein p53--metabolism<br/>Xenograft Model Antitumor Assays