TY - GEN AU - Sun,Haopeng AU - Xu,Xiaoli AU - Wu,Xiaowen AU - Zhang,Xiaojin AU - Liu,Fang AU - Jia,Jianmin AU - Guo,Xiaoke AU - Huang,Jingjie AU - Jiang,Zhengyu AU - Feng,Taotao AU - Chu,Hongxi AU - Zhou,You AU - Zhang,Shenglie AU - Liu,Zongliang AU - You,Qidong TI - Discovery and design of tricyclic scaffolds as protein kinase CK2 (CK2) inhibitors through a combination of shape-based virtual screening and structure-based molecular modification SN - 1549-960X PY - 2014///0321 KW - Casein Kinase II KW - antagonists & inhibitors KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Drug Design KW - Drug Evaluation, Preclinical KW - Humans KW - Models, Molecular KW - Naphthyridines KW - chemistry KW - Phenazines KW - Protein Conformation KW - Protein Kinase Inhibitors KW - Software KW - User-Computer Interface N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/ci400114f ER -