Lopes dos Santos, Mariana

Rebmab200, a humanized monoclonal antibody targeting the sodium phosphate transporter NaPi2b displays strong immune mediated cytotoxicity against cancer: a novel reagent for targeted antibody therapy of cancer. [electronic resource] - PloS one 2013 - e70332 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0070332 doi


Animals
Antibodies, Monoclonal--immunology
Antibodies, Monoclonal, Humanized--genetics
Antibody Specificity--immunology
Antibody-Dependent Cell Cytotoxicity--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Complement System Proteins--immunology
Female
Flow Cytometry
Humans
Immunohistochemistry
Kinetics
Mice
Neoplasms--drug therapy
Ovarian Neoplasms--drug therapy
Protein Binding--immunology
Sodium-Phosphate Cotransporter Proteins, Type IIb--antagonists & inhibitors
Surface Plasmon Resonance