Chang, Xiaofei

The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors. [electronic resource] - PloS one 2013 - e68966 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0068966 doi


Adaptor Proteins, Signal Transducing--genetics
Animals
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Female
Gefitinib
Humans
Immunoblotting
Kaplan-Meier Estimate
Lung--drug effects
Lung Neoplasms--drug therapy
Male
Mice
Middle Aged
Phosphatidylinositol 3-Kinases--metabolism
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Quinazolines--pharmacology
RNA Interference
Signal Transduction--drug effects
Tumor Suppressor Proteins--genetics
Xenograft Model Antitumor Assays